Cancer resistance of SR/CR mice in the genetic knockout backgrounds of leukocyte effector mechanisms: determinations for functional requirements

Abstract Background Spontaneous Regression/Complete Resistant (SR/CR) mice are a colony of cancer-resistant mice that can detect and rapidly destroy malignant cells with innate cellular immunity, predominately mediated by granulocytes.Our previous studies suggest that several effector mechanisms, such as perforin, granzymes, or complements, may be

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A Review on Information System Audit Using COBIT Framework

Information systems (IS) audit contains a proper review of risks associated along with the organization of information systems and processes.Also, an assessment of whether enough quality control will ensure the efficiency, effectiveness, integrity, and security of organization data and assets of the information system.An IS / IT audit is a coordina

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